Publications

Vu J, Tavasoli K, Sheedy C, Chowdhury S, Mandjikian L, Bacal J, Morrissey M, Richardson C*, Gardner B*. A genome-wide screen links peroxisome regulation with Wnt signaling throughRNF146 and TNKS/2. Journal of Cell Biology. 2024 October 07; 223(10):-. Link bioRxiv preprint: Link

Chowdhury SP, Solley SC, Polishchuk E, Bacal J, Conrad JE, Gardner BM, Acosta-Alvear D, Zappa F. Baseline Unfolded Protein Response Signaling Adjusts the Timing of the Mammalian Cell Cycle. Mol Biol Cell. 2024 Apr 24:mbcE23110419. Link

Miller ADC, Chowdhury SP, Hanson HW, Linderman SK, Ghasemi HI, Miller WD, Morrissey MA, Richardson CD, Gardner BM, Mukherjee A. Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types. J Biol Eng. 2024 Apr 22;18(1):30. Link

Ali BA, Judy RM, Chowdhury S, Jacobsen NK, Castanzo DT, Carr KL, Richardson CD, Lander GC, Martin A, Gardner BM. The N1 domain of the peroxisomal AAA-ATPase Pex6 is required for Pex15 binding and proper assembly with Pex1. J Biol Chem. 2024 Jan;300(1):105504. Link

Ghasemi HI, Bacal J, Yoon AC, Tavasoli KU, Cruz C, Vu JT, Gardner BM, Richardson CD. Interstrand crosslinking of homologous repair template DNA enhances gene editing in human cells. Nat Biotechnol. 2023 Oct;41(10):1398-1404. doi: 10.1038/s41587-022-01654-y. Link

Judy RM, Sheedy CJ, Gardner, BM. (2022) Insights into the Structure and Function of the Pex1/Pex6 AAA-ATPase in Peroxisome Homeostasis. Cells. 11(13), 2067. Link

Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic, G, Stefely MS, Hurley JH, Lander GC, Martin A. (2018) The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading. Nature Communications. 9(1): 135. PDF

Gardner BM, Chowdhury S, Lander GC, Martin A. (2015) The Pex1/Pex6 Complex is a Heterohexameric AAA+ Motor with Alternating and Highly Coordinated Subunits. Journal of Molecular Biology 427: 1375–1388. PDF

Gardner BM, Pincus D, Gotthardt K, Gallagher CM, and Walter P. (2013) Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response. Cold Spring Harbor Perspectives in Biology 1;5(3): a013169. PDF

Gardner BM and Walter P. (2011) Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science 333(6051): 1891-4. PDF